Chuck, Paul and the guys, are all set up for a night of girls, drinking and excitement. As Candy and car load of her girlfriends make their way to the house to realize their night of fun will soon turn into a night of terror. Candy plans to set up her cousin Melissa and her boyfriend Chuck for night of quick intimacy. But in the act of intimacy, something goes fatally wrong. As Melissa heart stops, the gang is forced, to make a quick decision. While Chuck, Candy and the gang decides to bury the body and leave the house, something strange begins to happen; as guests begin to disappear, they quickly discover that Melissa has come back from the dead. But at this time the roads are flooded and the power is out, it leaves the gang scurry to search for safety. Once Chuck, Paul and Candy has realize, that their friends are falling like flies around them and that Melissa is the murder, they finally escape and to wake up in a hospital. This leaves Dr. Ross to find out what and the reasons why.